Macro-dosing Psilocybin

Taking Psilocybin at a Macro-dose level, usually defined as between 2 and 3.5 grams of dried psilocybin mushrooms, has been shown in many scientifically meticulous studies to reliably produce spiritual, mystical, or transcendent experiences that have lasting positive effect on the subject. Studies at Harvard, Stanford, Yale, University of Toronto, and Johns Hopkins have begun to realize the drastic benefits of psilocybin in treating numerous psychological conditions. In addition to its remarkable effectiveness in treating depression, anxiety, and addiction, psilocybin also has the potential to radically improve the well-being and happiness of 'healthy' individuals. 

Humans can scientifically quantify many aspects of psilocybin metabolization, however we still lack crucial information as to why the bonding of psilocin with various 5HT receptors is able to produce metaphysical effects that are consistent across individuals of greatly varied backgrounds.

Positive Effects 

 

  • Sensory enhancement and synesthesia (mixing of senses) ex. hearing colours

  • Altered sense of time

  • Visual stimulation, closed eye pattern hallucination (often geometric patterns)

  • Unusual thought or speech patterns

  • Philosophical Ideation

  • Creative epiphanies

  • Heightened self awareness and perception

  • Personal insight and reflection

  • Excitement and euphoria

  • Out of body experiences

  • Communication with otherworldly entities

  • Bodily vibrations

 

Negative Effects

 

  • Temporary Cognitive impairment (in some aspects)

  • Anxiety (due to unusual thoughts or feelings)

  • Confusion (due to unsual thoughts or feelings)

  • Discomfort (due to unusual thoughts or feelings)

*Visualization of brain network connectivity*